Pharmacy

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Pharmacy

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EXTERNAL PROFILES

Associate Professor

Dr. Md. Saddam Hussain

Dr. Md. Saddam Hussain working as an Associate Professor at Noakhali Science and Technology University (NSTU), Bangladesh, with a PhD from the University of South Australia (2024) specializing in nanoparticle-based drug delivery systems. Mr. Hussain graduated top of his class in B.Pharm and M.Pharm from NSTU, earning the Prime Minister Gold Medal Award (2015). His research focuses on cancer therapeutics, pharmacogenomics, and natural product pharmacology, with over 40 publications in reputed journals (ACS Applied Materials & Interfaces, Heliyon). He has contributed to groundbreaking work on pH-responsive micelles and genetic polymorphisms in diseases, while actively mentoring students and collaborating with international institutions like ANSTO and UniSA. Recognized with awards like the Hard Yakka Award (2023), Dr. Hussain combines academic rigor with a passion for translational research to address global health challenges.

Pharmacy

BIOGRAPHY

Dr. Md. Saddam Hussain, born on May 7, 1991, in Bangladesh, is an accomplished Drug Delivery Scientist and Associate Professor at Noakhali Science and Technology University (NSTU), renowned for his groundbreaking research in nanomedicine and drug delivery systems. After earning his B.Pharm and M.Pharm from NSTU—where he graduated top of his class and received the Prime Minister Gold Medal. He completed his PhD (2024) at the University of South Australia, developing innovative pH-responsive micelles for cancer therapy. With over 40 publications in high-impact journals (e.g., ACS Applied Materials & Interfaces and International Journal of Pharmaceutics), his work spans nanotechnology, pharmacogenomics, and natural product pharmacology, including pioneering studies on oligoelectrolyte-mediated drug release and genetic markers in neuropsychiatric disorders. A recipient of the Hard Yakka Award (2023) and National Science and Technology Fellowship (2016), Dr. Hussain actively collaborates with global institutions like ANSTO and UniSA while mentoring future scientists at NSTU. His research bridges traditional medicine and cutting-edge nanotech, driven by a vision to translate lab discoveries into affordable healthcare solutions for Bangladesh and beyond.

RESEARCH INTERESTS
Pharmaceutics and Pharmaceutical Technology Formulation Development of Pharmaceuticals Drug Formulation Pharmaceutical Research and Development Controlled Drug Delivery Dosage Form Development Targeted Delivery Systems for the Cytotoxic Drugs Bio responsive Polymers and Nanomedicine Delivery Systems Novel Drug Loaded Site Specific and Responsive Hydrogel

2020 - 2024

Ph.D. (Medical Sciences)

CHS: Clinical and Health Sciences
University of South Australia

2015 - 2017

M.Pharm

Clinical Pharmacy and Pharmacology
Noakhali Science and Technology University

2010 - 2014

B.Pharm

Pharmacy
Noakhali Science and Technology University

2007 - 2009

HSC

Science
Chittagong Government College

Last updated on 2026-05-05 16:24:58

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2024-01-17
Cyber Security Awareness Training
Description: Enter Training Description
Organization: University of South Australia
2020-05-29
FreezerPro Online Training
Description: Online Training
Organization: University of South Australia
2020-02-27
Chemwatch GoldFFX Training
Description: • Access hazard information on chemicals • Maintain stores and manifests
Organization: Future Industries Institute, University of South Australia
2020-02-27
Safe Use and Handling of Liquid Nitrogen
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Organization: University of South Australia
2017-09-29
In-Plant Training
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Organization: BEXIMCO PHARMACEUTICALS LTD.
2015-06-20
Training on Basic Biotechnology
Description: Enter Training Description
Organization: National Institute of Biotechnology, Bangladesh
2018-11-28
Teaching-Learning Pedagogy
Description: Enter Training Description
Organization: Noakhali Science and Technology University, Bangladesh
2016-03-11
Computational Tools for Cancer Research
Description: Enter Training Description
Organization: Bangladesh Council of Scientific and Industrial Research (BCSIR), Bangladesh
AWARDS AND ACHIEVEMENTS

1

Hard Yakka Award-Always in the Lab

University of South Australia, Australia

2

Prime Minister Gold Medal Award, 2015

Government of the People's Republic of Bangladesh
2026
Journal

Correlation of Polymer--drug Composition with Micelle Properties, Performance, and Cytotoxicity for the Oligoelectrolyte-mediated pH-triggered Release of Hydrophobic Drugs

Authors: Md Saddam Hussain, Riya Khetan, Hugo Albrecht, Marta Krasowska, Anton Blencowe
Journal: Polymers
DOI: 10.3390/polym18020247
2026
Journal

Simultaneous Determination of Gliclazide and Montelukast in Rat Plasma by a Validated RP-HPLC Method and Its Application to a Pharmacokinetic Interaction Study

Authors: Israt Jahan Binta Elias, Md Mofazzel Hossain, Md Mamun Uddin, Shammi Shefa Un Nur Nishat, Mahmuda Ferdous, Prodip Kumar Baral, Md Saddam Hussain, Rita Bhatta, Abhijit Das
Journal: Separation Science Plus
DOI: org/10.1002/sscp.70212
2025
Journal

Exploring the toxicity and clinical outcomes of doxorubicin, cyclophosphamide, and taxane-based chemotherapies in women with breast cancer in Bangladesh

Authors: Md Shalahuddin Millat, Md Saddam Hussain, Arafat Miah, Md Abdul Barek, Mohammad Sarowar Uddin, Mahmuda Ferdous, Md Abdul Aziz, Md Mahmudul Hoque, Md Saiful Islam, Mohammad Safiqul Islam
Journal: Journal of Oncology Pharmacy Practice
DOI: 10.1177/10781552251377418
2025
Journal

Clinical insights into the role of smoking, diabetes, and rheumatoid arthritis in osteoporotic fractures

Authors: Hussain, Md Saddam and Islam, Tarequl and Islam, Md Safiqul and Haque, Md Azizul and others
Journal: Archives of Osteoporosis
DOI: http://dx.doi.org/10.1007/s11657-025-01575-8
2025
Journal

Influence of pendant pyridyl regioisomers on the pH-responsive behaviour of polymer-homopeptide copolymers and micelles

Authors: Dharmayanti, Cintya and Clulow, Andrew J and Gillam, Todd A and Klinger-Hoffmann, Manuela and Albrecht, Hugo and Blencowe, Anton
Journal: European Polymer Journal
DOI: http://dx.doi.org/10.1016/j.eurpolymj.2025.113931
2024
Journal

Association of NOTCH4 and CYP2E1 Genetic Variants With Schizophrenia in the Bangladeshi Population: A Case-Control Study

Authors: Millat, Md Shalahuddin and Roy, Joysree and Rahman, Md Atikur and Aziz, Md Abdul and Islam, Safiqul and Chowdhury, Md Mazharul Islam and Barek, Md Abdul and Hussain, Md Saddam and Uddin, Mohammad Sarowar and Siddiqui, Shafayet Ahmed and others
Journal: Health Science Reports
DOI: http://dx.doi.org/10.1002/hsr2.70262
2024
Journal

Oligoelectrolyte-mediated, pH-triggered release of hydrophobic drugs from non-responsive micelles: Influence of oligo (2-vinyl pyridine)-loading on drug-loading, release and cytotoxicity

Authors: Hussain, Md Saddam and Khetan, Riya and Albrecht, Hugo and Krasowska, Marta and Blencowe, Anton
Journal: International Journal of Pharmaceutics
DOI: http://dx.doi.org/10.1016/j.ijpharm.2024.124368
2024
Journal

Teaching an old dog new tricks: a global approach to enhancing the cytotoxicity of drug-loaded, non-responsive micelles using oligoelectrolytes

Authors: Saddam Hussain, Md and Khetan, Riya and Clulow, Andrew J and Ganesan, Raja and MacMillan, Alexander and Robinson, Nirmal and Ahmed-Cox, Aria and Krasowska, Marta and Albrecht, Hugo and Blencowe, Anton
Journal: ACS Applied Materials \& Interfaces
DOI: http://dx.doi.org/10.1021/acsami.3c16551
2023
Journal

Influence of Lyophilization and Cryoprotection on the Stability and Morphology of Drug-Loaded Poly (ethylene glycol-b-$\varepsilon$-caprolactone) Micelles

Authors: Hussain, Md Saddam and Faisal, Khandokar Sadique and Clulow, Andrew J and Albrecht, Hugo and Krasowska, Marta and Blencowe, Anton
Journal: Polymers
DOI: http://dx.doi.org/10.3390/polym15081974
2023
Journal

ZNF804A intronic variant rs1344706 and NGRN rs12807809 genetic polymorphisms and risk of schizophrenia in Bangladesh

Authors: Jafrin, Sarah and Aziz, Md Abdul and Sajal, Md and Akter, Tarzina and Das, Chaity and Akter, Tahmina and Hussain, Md Saddam and Millat, Md Shalahuddin and Uddin, Mohammad Sarowar and Naznin, Nura Ershad and others
Journal: Human Gene
DOI: http://dx.doi.org/10.1016/j.humgen.2023.201175
2022
Journal

TF and TCF4 gene polymorphisms are linked to autism spectrum disorder: a case--control study

Authors: Azmerin, Maria and Hussain, Md Saddam and Aziz, Md Abdul and Barek, Md Abdul and Begum, Mobashera and Sen, Niloy and Rahman, Md Abdur and Shahriar, Mohammad and Baeesa, Saleh Salem and Ashraf, Ghulam Md and others
Journal: Journal of International Medical Research
DOI: http://dx.doi.org/10.1177/03000605221138492
2022
Journal

Current antithrombotic therapies and prospects of natural compounds in the management of the thrombotic disorder

Authors: Mazumder, Tanoy and Salam, Md Abdus and Mitra, Shuvo and Hossain, Sayem and Hussain, Md Saddam
Journal: Natural Resources for Human Health
DOI: http://dx.doi.org/10.53365/nrfhh/154960
2022
Journal

A comparative evaluation of cardiac and neurological safety status of two commonly used oral hypoglycaemic agents in T2-DM Swiss albino mice model

Authors: Rahman, Md Ohidur and Ahmed, Shaheen and Mazumder, Tanoy and Salam, Md Abdus and Baral, Prodip Kumar and Rana, Md Faruk and Mitra, Shuvo and Hossain, Sayem and Rahman, Rubiya and Hussain, Md Saddam
Journal: Metabolism Open
DOI: http://dx.doi.org/10.1016/j.metop.2022.100191
2021
Journal

Risk of type 2 diabetes mellitus and cardiovascular complications in KCNJ11, HHEX and SLC30A8 genetic polymorphisms carriers: a case-control study

Authors: Aka, Tutun Das and Saha, Urmi and Shati, Sayara Akter and Aziz, Md Abdul and Begum, Mobashera and Hussain, Md Saddam and Millat, Md Shalahuddin and Uddin, Mohammad Sarowar and Islam, Mohammad Safiqul
Journal: Heliyon
DOI: http://dx.doi.org/10.1016/j.heliyon.2021.e08376
2021
Journal

Long-term use of proton pump inhibitors adversely affects minerals and vitamin metabolism, bone turnover, bone mass, and bone strength

Authors: Hussain, Md Saddam and Mazumder, Tanoy
Journal: Journal of basic and clinical physiology and pharmacology
DOI: http://dx.doi.org/10.1515/jbcpp-2021-0203
2021
Journal

Alterations of serum trace elements and other biochemical parameters are correlated with the pathogenesis of systemic lupus erythematosus: A preliminary study on Bangladeshi population

Authors: Jahan, Israt and Das, Dalim Chandra and Hussain, Md Saddam and Hossain, Md Monir and Chowdhury, Muhammed Alamgir Zaman and Fardous, Zeenath and Rahman, Md Mujibur and Kabir, AKM Humayun and Deb, Sudip Ranjan and Siddique, Md Abu Bakar and others
Journal: Journal of Trace Elements in Medicine and Biology
DOI: http://dx.doi.org/10.1016/j.jtemb.2021.126861
2021
Journal

A case-control study investigating the association of TP53 rs1042522 and CDH1 rs16260 polymorphisms with prostate cancer risk

Authors: Akter, Rabeya and Islam, Md Siddiqul and Islam, Md Safiqul and Aziz, Md Abdul and Hussain, Md Saddam and Millat, Md Shalahuddin and Uddin, Mohammad Sarowar and Islam, Mohammad Safiqul
Journal: Meta Gene
DOI: http://dx.doi.org/10.1016/j.mgene.2021.100962
2021
Journal

Comparative lipid and uric acid suppressing properties of four common herbs in high fat-induced obese mice with their total phenolic and flavonoid index

Authors: Mazumder, Tanoy and Mamun, Imran Parvez and Zaman, Md Safayat and Islam, AKM Khairul and Chowdhury, Shahjalal and Reza, Md Sharif and Hussain, Md Saddam
Journal: Biochemistry and biophysics reports
DOI: http://dx.doi.org/10.1016/j.bbrep.2021.100990
2021
Journal

CNTNAP2 gene polymorphisms in autism spectrum disorder and language impairment among Bangladeshi children: a case--control study combined with a meta-analysis

Authors: Uddin, Mohammad Sarowar and Azima, Atkia and Aziz, Md Abdul and Aka, Tutun Das and Jafrin, Sarah and Millat, Md Shalahuddin and Siddiqui, Shafayet Ahmed and Uddin, Md Giash and Hussain, Md Saddam and Islam, Mohammad Safiqul
Journal: Human Cell
DOI: https://doi.org/10.1007/s13577-021-00546-8
2021
Journal

A comprehensive review of pharmacological and toxicological properties of Cheilocostus speciosus (J. Koenig) CD Specht

Authors: Hussain, MD Saddam and Mazumder, Tanoy
Journal: Trends in Phytochemical Research
2020
Journal

Genetic variants of ZNF385B and COMT are associated with autism spectrum disorder in the Bangladeshi children

Authors: Uddin, Md Giash and Siddiqui, Shafayet Ahmed and Uddin, Mohammad Sarowar and Aziz, Md Abdul and Hussain, Md Saddam and Millat, Md Shalahuddin and Sen, Niloy and Muhuri, Basana and Islam, Mohammad Safiqul and others
Journal: Meta Gene
DOI: https://doi.org/10.1016/j.mgene.2020.100820
2020
Journal

Exploration of in vitro thrombolytic, anthelminthic, cytotoxic and in vivo anxiolytic potentials with phytochemical screening of flowers of Brassica nigra

Authors: Uddin, Mohammad Sarowar and Millat, Md Shalahuddin and Islam, Mohammad Safiqul and Hussain, Md Saddam and Uddin, Md Giash and Siddiqui, Shafayet Ahmed and Ferdous, Mahmuda
Journal: Future Journal of Pharmaceutical Sciences
DOI: https://doi.org/10.1186/s43094-020-00099-x
2020
Journal

A clinical evaluation of the alterations in the level of serum zinc, copper, iron, and manganese in the ischemic heart disease patients of Bangladesh-A case-control study

Authors: Anonna, Shamima Nasrin and Ahamed, Sayed Koushik and Uddin, Md Giash and Adnan, Md Tarek and Uddin, SM Naim and Hussain, Md Saddam and Millat, Md Shalahuddin and Bulbul, Latifa and Bhatta, Rita and Sarwar, Md Shahid and others
Journal: Heliyon
DOI: https://doi.org/10.1016/j.heliyon.2020.e05311
2020
Journal

Association of DRD2 gene polymorphisms with schizophrenia in the young Bangladeshi population: A pilot study

Authors: Hussain, Md Saddam and Siddiqui, Shafayet Ahmed and Mondal, Susmita and Millat, Md Shalahuddin and Marzan, Sadiatul and Uddin, Md Giash and Aziz, Md Abdul and Alam, Md Faruq and Islam, Mohammad Safiqul
Journal: Heliyon
DOI: https://doi.org/10.1016/j.heliyon.2020.e05125
2020
Journal

Association of rs363598 and rs360932 polymorphisms with autism spectrum disorder in the Bangladeshi children

Authors: Aziz, Md Abdul and Akter, Tahmina and Hussain, Md Saddam and Millat, Md Shalahuddin and Uddin, Mohammad Sarowar and Sajal, Md and Jafrin, Sarah and Aka, Tutun Das and Akter, Tarzina and Das, Chaity and others
Journal: Meta Gene
DOI: https://doi.org/10.1016/j.mgene.2020.100733
2020
Journal

Evaluation of phytochemical and pharmacological properties of seeds of Momordica charantia

Authors: Zahan, Sumyya and Uddin, SM Naim and Hossain, Mohammed Kamrul and Mannan, Afifa Binthe and Rahman, Minhajur and Chen, Umay and Mazumder, Tanoy and Uddin, AHM Mazbah and Arefin, Sayema and Hussain, Md Saddam and others
Journal: Avicenna Journal of Phytomedicine
2019
Journal

In-vivo and in-vitro evaluation of pharmacological activities of Ardisia solanacea leaf extract

Authors: Islam, Mohammad Rashedul and Naima, Jannatul and Proma, Nawreen Monir and Hussain, Md Saddam and Uddin, SM Naim and Hossain, Mohammed Kamrul
Journal: clinical phytoscience
DOI: https://doi.org/10.1186/s40816-019-0128-9
2019
Journal

Neuropharmacological evaluation of methanolic extract of Costus speciosus Linn. rhizome in Swiss albino mice

Authors: Chen, Umay and Hussain, Md Saddam and Mazumder, Tanoy and Uddin, SM Naim and Banik, Sujan
Journal: Asian Pacific Journal of Tropical Biomedicine
DOI: http//10.4103/2221-1691.259002
2019
Journal

Antihyperlipidemic screening and plasma uric acid reducing potential of Momordica charantia seeds on Swiss albino mice model

Authors: Hussain, Md Saddam and Jahan, Nusrat and Rashid, Md Mamun Or and Hossain, Mohammad Salim and Chen, Umay and Rahman, Naimur
Journal: Heliyon
DOI: https://doi.org/10.1016/j.heliyon.2019.e01739
2019
Journal

How the association between obesity and inflammation may lead to insulin resistance and cancer

Authors: Amin, Mohammad Nurul and Hussain, Md Saddam and Sarwar, Md Shahid and Moghal, Md Mizanur Rahman and Das, Abhijit and Hossain, Mohammad Zahid and Chowdhury, Jakir Ahmed and Millat, Md Shalahuddin and Islam, Mohammad Safiqul
Journal: Diabetes and metabolic syndrome: clinical research \& reviews
DOI: https://doi.org/10.1016/j.dsx.2019.01.041
2019
Journal

Increased concentration of serum MDA, decreased antioxidants and altered trace elements and macro-minerals are linked to obesity among Bangladeshi population

Authors: Adnan, Md Tarek and Amin, Mohammad Nurul and Uddin, Md Giash and Hussain, Md Saddam and Sarwar, Md Shahid and Hossain, Md Kamrul and Uddin, SM Naim and Islam, Mohammad Safiqul
Journal: Diabetes and Metabolic Syndrome: Clinical Research \& Reviews
DOI: https://doi.org/10.1016/j.dsx.2018.12.022
2018
Journal

An in vivo study of the pharmacological activities of a methanolic acetate fraction of Pistia stratiotes L.: An ethno-medicinal plant used in Bangladesh

Authors: Hussain, Md Saddam and Ibrahim, Md and Hasan, Md Murad and Aziz, Mohammad Tarek and Suchi, Suzia Akter and Uddin, Md Giash
Journal: Animal Models and Experimental Medicine
DOI: https://doi.org/10.1002/ame2.12037
2018
Journal

Evaluation of psychopharmacological and neurosafety profile of Swas Kas Chintamani Ras (SKC) in Swiss-Webster mice

Authors: Islam, Tarequl and Hussain, Md Saddam and Amin, Mohammad Nurul and Tuhin, Ashraful Mahmud
Journal: Avicenna Journal of Phytomedicine
2018
Journal

Ascertainment of pharmacological activities of Allamanda neriifolia Hook and Aegialitis rotundifolia Roxb used in Bangladesh: An in vitro study

Authors: Hasan, Imam and Hussain, Md Saddam and Millat, Md Shalahuddin and Sen, Niloy and Rahman, Md Abdur and Rahman, Md Atikur and Islam, Safiqul and Moghal, Md Mizanur Rahman
Journal: Journal of traditional and complementary medicine
DOI: https://doi.org/10.1016/j.jtcme.2017.03.005
2018
Journal

An in vivo study regarding analgesic and anxiolytic activity of methanolic extract of Typha elephantina Roxb

Authors: Sen, Niloy and Bulbul, Latifa and Hussain, Md Saddam and Banik, Sujan and Choudhuri, Md Shahbuddin Kabir
Journal: Clinical phytoscience
DOI: https://doi.org/10.1186/s40816-018-0061-3
2017
Journal

Investigation of in vitro thrombolytic and anti-helminthic activity and in vivo anxiolytic and antidepressant potentiality with phytochemical nature of methanolic extract of Leucas lavandulifolia

Authors: Islam, Areful and Hussain, Md Saddam and Sen, Niloy and Abedin, Fokhrul and Millat, Md Shalahuddin and Islam, Mohammad Safiqul and Das, Abhijit and Kar, Auditi and Hossain, Md Monir
Journal: Sustainable Chemistry and Pharmacy
DOI: https://doi.org/10.1016/j.scp.2017.09.001
2017
Journal

Elevated serum MDA and depleted non-enzymatic antioxidants, macro-minerals and trace elements are associated with bipolar disorder

Authors: Chowdhury, Manjurul Islam and Hasan, Maimuna and Islam, Mohammad Safiqul and Sarwar, Md Shahid and Amin, Mohammad Nurul and Uddin, SM Naim and Rahaman, Md Zahedur and Banik, Sujan and Hussain, Md Saddam and Yokota, Kazushige and others
Journal: Journal of Trace Elements in Medicine and Biology
DOI: https://doi.org/10.1016/j.jtemb.2016.09.012
2017
Journal

Characterization of phytoconstituents and evaluation of antimicrobial activity of silver-extract nanoparticles synthesized from Momordica charantia fruit extract

Authors: Rashid, Md Mamun Or and Akhter, Kazi Nahid and Chowdhury, Jakir Ahmed and Hossen, Foysal and Hussain, Md Saddam and Hossain, Md Tanvir
Journal: BMC complementary and alternative medicine
DOI: https://doi.org/10.1186/s12906-017-1843-8
2017
Journal

Tartrazine induced changes in physiological and biochemical parameters in Swiss albino mice, Mus musculus

Authors: Arefin, Sayema and Hossain, Mohammad Salim and Neshe, Shamme Akter and Rashid, Md Mamun Or and Amin, Mohammad Tohidul and Hussain, Md Saddam
Journal: Marmara Pharmaceutical Journal
DOI: https://doi.org/10.12991/marupj.319304
2016
Journal

In-vitro and in-vivo pharmacological activities with phytochemical evaluation of methanolic extract of Microcos paniculata stem barks

Authors: Sarker, Md Al-Amin and Banik, Sujan and Hussain, Md Saddam and Ghosh, Antara and Hossain, Mohammad S
Journal: Curr Drug Ther
DOI: https://doi.org/10.2174/1574885511666160520154529
2023
Conference

Engineering polymeric micelles for endosomal drug delivery

Authors: Blencowe A, Hussain MS, Brewer K, Dharmayanti C, Krasowska M, Albrecht H
2022
Conference

Rendering non-responsible micelles pH-responsive through the incorporation of oligoelectrolytes

Authors: Hussain MS, Albrecht H, Krasowska M, Blencowe A
2017
Conference

Histological and antihyperlipidemic screening along with plasma uric acid reducing potential of ethanolic extract of Momordica charantia seeds on swiss albino mice model

Authors: Hussain MS, Lira N, Rashid MM, Hossain MS, Rahman N
DOI: https://doi.org/10.1016/j.bcp.2017.06.006
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Masters - 2022-23

Israt Jahan Naziha

Thesis Student

Thesis Title: Functional Consequences of Long-Term Pantoprazole Use on Musculoskeletal Health and Major Organs in Rat Model: Role of Fructooligosaccharide (FOS) in Physiological Recovery and Enhanced Minerals Absorption

Overview: Enter Project/Thesis Overview

Honors - 2018-19

Sumita Akter Sumi

Thesis Student

Thesis Title: Differential Evaluation of Behavioral and Somatic Outcomes of Colchicine and Its Botanical Source Gloriosa superba in Glucocorticoid- Stressed Mice

Overview: Enter Project/Thesis Overview

SOCIAL PROFILES

Department

Pharmacy

Noakhali Science and Technology University