EXTERNAL PROFILES
Assistant Professor
Md. Abdur Rahman
Md. Abdur Rahman (B. Pharm, M. Pharm) is an Assistant Professor in the Department of Pharmacy at Noakhali Science and Technology University (NSTU), Bangladesh. He earned both his Bachelor and Master of Pharmacy degrees from NSTU, majoring in Clinical Pharmacy and Pharmacology. His research focuses on pharmaceutical technology, molecular biology, and pharmacogenomics, with special interest in developing plant-based formulations and evaluating their protective effects in disease models. Before joining academia, he worked as a Senior Production Officer at Advanced Chemical Industries (ACI) Limited, gaining extensive industrial experience. He has co-authored several peer-reviewed publications and actively participates in national scientific conferences and training programs related to biotechnology and pharmaceutical research.
Pharmacy
BIOGRAPHY
Md. Abdur Rahman (B. Pharm, M. Pharm) is an Assistant Professor in the Department of Pharmacy at Noakhali Science and Technology University (NSTU), Bangladesh. He specializes in Pharmaceutical Technology, Molecular Biology, and Pharmacogenomics, focusing on how molecular signatures influence drug response and disease mechanisms. He completed both his Bachelor and Master of Pharmacy degrees from NSTU, majoring in Clinical Pharmacy and Pharmacology, with research on the IMMP2L gene and autism susceptibility in the Bangladeshi population. Before joining academia, he worked as a Senior Production Officer at Advanced Chemical Industries (ACI) Ltd., where he gained extensive industrial experience in pharmaceutical manufacturing and GMP practices. His current research explores plant-based pharmaceutical formulations and their hepatoprotective, cardioprotective, thyroprotective, and nephroprotective effects using modern pharmacological and molecular techniques. He has co-authored several papers in reputed journals such as Life Sciences and Molecular Biotechnology. Rahman actively participates in national conferences and training programs, contributing to the advancement of precision medicine and pharmacogenomic research in Bangladesh.
RESEARCH INTERESTS
2014 - 2015
Master of Pharmacy
Department of Pharmacy
Noakhali Science and Technology University
Thesis: cGPA-3.84
2010 - 2013
Bachelor of Pharmacy
Department of Pharmacy
Noakhali Science and Technology University
Thesis: cGPA-3.71
2006 - 2008
H.S.C
Science
Kabi Nazrul Government College, Dhaka.
Thesis: cGPA-5.00
2005 - 2006
S.S.C
Science
Jatrabari PDB High School, Dhaka.
Thesis: cGPA-4.63
Last updated on 2025-10-27 17:35:03
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2016-02-06
Training on Basic Bio-Technology
Description: Learned about basic activities related to biotechnological operations practically.
Organization: National Institute of Biotechnology (NIB), Ganakbari, Ashulia, Savar, Dhaka-13, Bangladesh.
2015-10-18
Basic In-plant Pharmaceutical Training
Description: Learned about basic principle & operating procedure of all pharmaceutical activities practically.
Organization: Novartis (Bangladesh) Limited, Cherag Ali Market, Tongi, Gazipur, Bangladesh.
2016-03-11
Workshop on Computational Tools for Cancer Research
Description: Learned about computational technique to perform experiment related to cancer, cancer related information, current scenario, causes, treatment, prevention of cancer and so many on.
Organization: Bangladesh Council of Scientific and Industrial Research (BCSIR) Lab, Chittagong Cantonment, Chittagong-4220, Bangladesh.
AWARDS AND ACHIEVEMENTS
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2024
Journal
Regulatory roles of MicroRNAs in the pathogenesis of metabolic syndrome
Authors: Md. Abdur Rahman, Md. Mahmodul Islam, Md. Abdur Rahman Ripon, Md. Monirul Islam, Mohammad Salim Hossain
Journal: Molecular Biotechnology
DOI: 10.1007/s12033-023-00805-z
2023
Journal
Formulation of Self Micro-Emulsifying Dry Powder of Zingiber officinale (Rhizome) and Its Effect on Hepatoprotective Activity in Mice Model
Authors: Md. Shariful Islam, Md. Abdur Rahman, Imtiaz Ahmed and Mohammad Salim Hossain
Journal: Bangladesh Pharmaceutical Journal
DOI: 10.3329/bpj.v26i2.67801
2023
Journal
Gut microbiota in obesity and related complications: unveiling the complex interplay
Authors: Md. Monirul Islam, Md. Mahmodul Islam, Md. Abdur Rahman, Md. Abdur Rahman Ripon, Mohammad Salim Hossain
Journal: Life sciences
DOI: 10.1016/j.lfs.2023.122211
2022
Journal
TF and TCF4 gene polymorphisms are linked to autism spectrum disorder: a case--control study
Authors: Maria Azmerin, Md. Saddam Hussain, Md. Siddiqul Islam, Md. Abdul Aziz, Md. Mizanur Rahman Moghal, Mobashera Begum, Niloy Sen, Md. Abdur Rahman, Mohammad Shahriar, Ghulam Md Ashraf, Mohammad Safiqul Islam
Journal: Journal of International Medical Research
DOI: 10.1177/030006052211384
2020
Journal
Investigation of hemotoxicologic potential of an ayurvedic preparation Kutajarista used in Sprue syndrome after chronic administration to male Sprague-Dawley rats
Authors: Mohammad Tohidul Amin, Kaniz Fatema, Palash karmakar, Md. Abdur Rahman, Tazmel Haque and M. Shahabuddin Kabir Choudhuri
Journal: African Journal of Pharmacy and Pharmacology
DOI: 10.5897/AJPP2020.5174
2018
Journal
Ascertainment of pharmacological activities of Allamanda neriifolia Hook and Aegialitis rotundifolia Roxb used in Bangladesh: An in vitro study
Authors: Imam Hasan, Md. Saddam Hussain, Md. Shalahuddin Millat, Niloy Sen, Md. Abdur Rahman, Md. Atikur Rahman, Safiqul Islam, Md. Mizanur Rahman Moghal
Journal: Journal of traditional and complementary medicine
DOI: 10.1016/j.jtcme.2017.03.005
2017
Journal
Elucidation of membrane stabilizing potentials of methanolic extract of Vigna unguiculata (cowpea) linn (seed)
Authors: Md. Saddam Hussain, Mohammad Salim Hossain, Niloy Sen, Md. Abdur Rahman, Md. Abdul Halim
Journal: Discovery Phytomedicine
DOI: 10.15562/phytomedicine.2017.35
2017
Journal
Elucidation of in-vitro thrombolytic, membrane stabilizing, cytotoxic activities and phytochemical nature of Bruguiera cylindrica leaves
Authors: Safiqul Islam, Md. Shalahuddin Millat, Md. Saddam Hussain, Md. Abdur Rahman, Md. Mizanur Rahman Moghal, Jasmin Ara Nipa, Imam Hasan, Meer Hossain.
Journal: Biology, Engineering, Medicine and Science Reports
DOI: 10.5530/PTB.2017.3.2
2016
Journal
Screening of Antimicrobial activities of methanolic extracts of Avicennia marina leaves and barks
Authors: S. M. Naim Uddin, Md. Shalahuddin Millat, Md. Abdur Rahman, Md. Khorshed Alam, Md. Mizanur Rahman Mogha
Journal: World Journal of Pharmaceutical Sciences
DOI: ISSN: 2321-3086
2016
Journal
Exploration of In-vitro antimicrobial and cytotoxic potentials of crude methanolic extracts of Quisqualis indica (stem bark): An ethno medicinal plant
Authors: Meer Hossain, Md. Saddam Hussain, Moin-Ul-Islam, Md. Abdur Rahman, Md. Shalahuddin Millat, Mirza Nusrat Sweety.
Journal: International Journal of Biological Research
DOI: 10.14419/ijbr.v4i2.6803
2016
Journal
Screenings of In-vitro antimicrobial, cytotoxic and anti-inflammatory activity of crude methanolic extracts of Crinum latifolium (Leaves)
Authors: Md. Abdur Rahman, Md. Saddam Hussain, Md. Shalahuddin Millat, Mithun Chandra Ray, Mohammad Tohidul amin and Md. Mizanur Rahman Mogha
Journal: Journal of Medicinal Plants Research
DOI: 10.5897/JMPR2016.6204
2016
Journal
Evaluation of In Vitro Antimicrobial and Anti-Inflammatory Potentials of Crude Methanolic Extracts of Excoecaria agallocha (Leaves)
Authors: Md. Abdur Rahman, Md. Saddam Hussain, Md. Shalahuddin Millat, Md. Mizanur Rahman Moghal
Journal: International Journal of Pharmacology, Phytochemistry and Ethnomedicine
DOI: 10.18052/www.scipress.com/IJPPE.5.25
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Masters - 2021-22
S.M Shohel
Executive in Pharma Industry
Thesis Title: Self Micro Emulsifying Drug Delivery System of Garlic Extract: An Emerging Approach for the Prevention of Cardiac Toxicity in Mice Model Through the Assessment of Pro-apoptotic Gene Expression
Overview: Cardiovascular disease (CVD) remains the leading cause of death worldwide. Due to their therapeutic benefits and minimal side effects, natural products such as herbs and spices are increasingly used in CVD management, alongside conventional drugs and procedures. This study evaluated the cardioprotective potential of garlic extract formulated in a self-microemulsifying drug delivery system (SMEDDS), using sodium fluoride (NaF) as a model cardiotoxic agent. Four different SMEDDS formulations were prepared with varying excipient ratios to assess their suitability for effective delivery. Evaluation tests, including flow property, visual inspection, self-emulsification time, stability test, SEM analysis, and Zeta potential, were performed on all formulations, and the findings were all good. Group II was characterized as a toxicant control group treated with NaF orally at a dose of 12 mg/kg BWT daily. Group I served as the normal control with no treatment, while Group II received NaF (12 mg/kg) to induce cardiac toxicity. Group III was treated with raw garlic extract (50 mg/kg), and Group IV received both NaF and raw garlic extract simultaneously. Groups V to VIII were given NaF (12 mg/kg) along with four different SMEDDS-formulated garlic powders (90 mg/kg). After 28 days of treatment, the SMEDDS groups (V–VIII) showed a significant (p < 0.05) reduction in cardiac biomarkers such as TC, LDL, and TG, and an increase in HDL compared to the toxicant control, indicating the cardioprotective effect of the SMEDDS garlic formulations. Cardiac dysfunction is closely linked to the expression of pro-inflammatory cytokines and apoptotic markers, which play pivotal roles in heart disease pathophysiology. This study examines the expression levels in cardiac tissue of important genes implicated in inflammation and apoptosis, namely IL-6, TNF-alpha, α and MCP-1.The expression of these genes is quantified using real-time PCR in various cardiac conditions, including ischemia-reperfusion injury and heart failure models. Our findings reveal a significant downregulation of these genes in treatment group compared to toxicant control group, highlighting their potential role in the progression of cardiac pathology.
Honors - 2018-19
Md. Hemal Mia
Lecturer in a Private College
Thesis Title: Dietary Influence on IBS, IBD, and CRC: A Comprehensive Review of Pathogenesis, Risk, and Therapeutic Potential
Overview: Major gastrointestinal (GI) disorders like Irritable Bowel Syndrome (IBS), Inflammatory Bowel Disease (IBD), and Colorectal Cancer (CRC) are becoming more prevalent worldwide, and there is growing evidence that diet plays a significant role in their etiology, progression, and treatment. The literature linking the onset and clinical course of these disorders to dietary patterns and nutritional components is thoroughly assessed in this study. FODMAPs, high-fat meals, and low fiber consumption are dietary triggers that affect gut-brain signaling, motility, and microbiota composition. These triggers are strongly linked to IBS, a functional gastrointestinal condition marked by changed bowel habits and abdominal pain. There is evidence that dietary interventions, like a low-FODMAPS diet and more soluble fiber, can effectively modulate symptoms and may even be more beneficial than pharmaceutical therapies in certain populations. IBD, which includes Crohn's disease and ulcerative colitis, is caused by a complicated interaction between environmental factors and genetic predisposition, with nutrition having both beneficial and detrimental effects. While diets high in fiber, fish, and plant-based nutrients show inverse relationships with illness flares, high intakes of red meat, animal fat, refined carbs, and processed foods have been linked to elevated risk. Mechanistically, these diets change antigen presentation and cytokine signaling, especially through Toll-like receptor pathways, which leads to gut dysbiosis, increased intestinal permeability, and heightened immunological responses. IBD and colorectal cancer (CRC), the third most prevalent cancer diagnosed globally, share pathophysiological processes, such as microbial dysbiosis and chronic inflammation. Increased prevalence of colorectal cancer is associated with Western dietary patterns, which are characterized by a high intake of red and processed meats, alcohol, and a low intake of whole grains and fiber. Bile acid metabolism, dietary carcinogens, and reduced butyrate production by the gut microbiota can all contribute to carcinogenesis. On the other hand, anti-inflammatory diets such as the Mediterranean or ketogenic diets, as well as fasting or fasting-mimicking diets (FMDs), have shown promise in altering metabolic and epigenetic pathways, reducing cancer growth, and improving treatment outcomes.A common feature throughout these three disorders is the critical function of the gut microbiota as a mediator between disease and food. Symptom severity, immunological activation, and carcinogenesis are all associated with dysbiosis, decreased microbial diversity, and pathogenic changes. The necessity for precision nutrition strategies based on individual genetic, microbiological, and metabolic profiles is emphasized in this review, which also highlights diet as a key component of prevention and therapeutic management, in addition to being a contributing factor to disease.
Honors - 2018-19
Zannatul Nayem Mukta
House Wife
Thesis Title: Self-Micro Emulsifying Drug Delivery System (SMEDDS) of Mucuna pruriens Seeds Extract: An Emerging Approach for the Repression of Kidney Damages in Cisplatin Induced Mice Model
Overview: A serious worldwide health issue, chronic kidney disease (CKD) causes progressive renal deterioration as well as rising rates of morbidity and mortality. The use of natural medicines, such as medicinal plants, has received attention because of their therapeutic potential and fewer side effects. Cisplatin as a common nephrotoxic agent, the current work performed to determine the nephroprotective potential of Mucuna pruriens extract prepared utilizing a Self-micro–Emulsifying Drug Delivery System (SMEDDS) in mice model. A variety of characterization tests, such as flow property analysis, visual assessment, self-emulsification time, stability studies, scanning electron microscopy (SEM) analysis, and zeta potential measurement, were performed on four distinct SMEDDS formulations of Mucuna pruriens extract using different ratios of excipients. All of these tests produced satisfactory results. Forty Swiss albino mice weighing between (22-25g) were split into eight groups at random, each containing six mice. Group I was the normal control group, receiving no therapy. Group II was the toxicant control group, receiving intraperitoneal Cisplatin at a dose of 7.5 mg/kg body weight. Group III was given only Mucuna pruriens extract (400 mg/kg BWT) while Group IV was given the identical dosages of raw Mucuna pruriens extract and Cisplatin. Cisplatin and four different SMEDDS-based Mucuna pruriens formulations (7.5 mg/kg + 960 mg/kg BWT) were given to Groups V–VIII. When compared to the toxicant control group, the SMEDDS-treated groups (Groups V–VIII) showed significant (p<0.05) improvements in renal biomarkers like BUN, serum creatinine, and uric acid as well as histopathological improvements. Our experiment confirmed the nephroprotective efficacy of SMEDDS-based Mucuna pruriens formulations against nephrotoxicity caused by cisplatin.
Honors - 2017-18
Md. Riaz Uddin
Executive in Pharma Industry
Thesis Title: Nephroprotective Effect of Self Micro-Emulsifying Drug Delivery System (SMEDDS) of Methanolic Extract of Curcuma longa( Turmeric) Against Doxorubicin Induced Nephrotoxicity in Mice Model
Overview: Chronic kidney disease (CKD) is the leading cause of death globally. Despite the fact that some medications and mechanical methods are employed, natural products like herbs and spices are increasingly preferred for treating CKD because of their pharmacological benefits and lack of side effects. The purpose of this current study was to examine the potential nephroprotective effects of turmeric extract through Self-micro Emulsifying Drug Delivery System (SMEDDS) on mice models using doxorubicin as a standard nephrotoxic drug. Four different SMEDDS formulations of turmeric extract were prepared using different excipient ratios and underwent various evaluative tests like flow property, visual inspection, self-emulsification time, stability test, SEM analysis & amp zeta potential in order to characterize all formulations and showed satisfactory results for all tests performed. Forty-eight Swiss albino mice (20-35 g), were randomly divided into eight groups each of which consisted of six mice. Group I was the normal control group, where the animals received no treatment and Group II was defined as a toxicant control group treated with doxorubicin IP route at a dose of 3 mg/kg BWT twice in a week . On the other hand, Group III was given raw turmeric extract only (100 mg/kg BWT) in contrast with Group IV, which was treated with both doxorubicin + raw turmeric extract (same time, same dose used previously). Group V-VIII received doxorubicin by IP route and 4 differently formulated turmeric powders by orally (3 mg/kg + 240 mg/kg). The duration of the experiment was 21 days. Formulated powder groups (Group V-VIII) exhibited a remarkable decrease in kidney biomarkers like urea, creatinine, and albumin was observed in these groups compared with the toxicant control group which revealed the nephro-protectivity of self-micro emulsifying formulation of turmeric extract against kidney injury.
Honors - 2017-18
Sajib Singha
Executive in Pharma Industry
Thesis Title: Assessment Of Enhanced Nephroprotective Efficacy Of Cuminum Cyminum with Self Micro-Emulsifying Drug Delivery System Against Doxorubicin Induced Nephrotoxicity In Swiss Albino Mice
Overview: Objective: Nephrotoxicity refers to kidney damage caused by harmful substances. Doxorubicin is a chemotherapeutic agent known for its nephrotoxic effects, which can lead to impaired renal function and potential kidney failure. This study aimed to evaluate the enhanced nephroprotective efficacy of Cuminum cyminum (cumin) formulated with a Self Micro-Emulsifying Drug Delivery System (SMEDDS) against doxorubicin-induced nephrotoxicity in male Swiss albino mice, focusing on renal function preservation. Materials and Methods: The SMEDDS formulations of cumin were prepared by mixing cumin extract with olive oil, Tween 80, PEG 400, Aerosil, and microcrystalline cellulose in different ratios. These formulations were evaluated thoroughly for temperature and centrifugal stability, with no phase separation or precipitation observed. Zeta potential measurements for all formulations ranged from -57.4 mV to -63 mV, indicating good stability. SEM analysis confirmed smooth particle distribution. Male Swiss albino mice were divided into eight groups: a normal control group, a toxic control group treated with doxorubicin, a cumin extract-treated group, and five treatment groups combining cumin SMEDDS formulations with doxorubicin. Kidney function was assessed by measuring serum creatinine, urea, and albumin levels, ensuring comprehensive data collection Results: The toxic control group had significantly higher serum creatinine and urea levels than the normal control group, confirming severe nephrotoxicity (p < 0.001). Cumin extract alone exhibited mild protective effects. Among the SMEDDS formulations, C-1 demonstrated the most significant nephroprotection (p < 0.001), showing the greatest reduction in serum creatinine and urea levels, followed by C-3, C-2, and C-4. Additionally, the C-1 formulation maintained higher serum albumin levels, indicating better overall kidney function preservation. Notably, C-1 demonstrated superior overall protective efficacy Conclusion: The significant improvement in serum creatinine, urea, and albumin levels suggests that SMEDDS could be a highly promising approach for delivering nephroprotective agents, offering superior protection compared to cumin extract alone. This merits further research for potential clinical applications.
Honors - 2017-18
Md Mokabbir Hossain Uchsas
Executive in Pharma Industry
Thesis Title: Evaluation of Nephroprotective Effect of Clove in Swiss Albino Mice Exposed to Doxorubicin
Overview: Nephrological disease is the leading cause of death globally. Despite the fact that some medications and mechanical methods are employed, natural products like herbs and spices are increasingly preferred for treating Nephrology disorder because of their pharmacological benefits and lack of side effects. The purpose of this current study was to examine the potential nephroprotective effects of Syzygium aromaticum-Clove extract through Self-micro–Emulsifying Drug Delivery System (SMEDDS) on mice models using Doxorubicin as a standard nephrotoxic drug. Four different SMEDDS formulations of clove extract were prepared using different excipient ratios and underwent various evaluative tests like flow property, visual inspection, self-emulsification time, stability test, SEM analysis & amp; Zeta potential in order to characterize all formulations and showed satisfactory results for all tests performed. Forty Swiss albino mice (20-30 gm), were randomly divided into eight groups each of which consisted of five mice. Group I was the normal control group, where the animals received no treatment and Group II was defined as a toxicant control group treated with Doxorubicin intraperitoneal at a dose of 3mg/kg BWT 2 times weekly. On the other hand, Group III was given raw Syzygium aromaticum-Clove extract only (150 mg/kg BWT) in contrast with Group IV, which was treated with both Doxorubicin raw Clove extract (same time, same dose used previously). Group V-VIII received intraperitoneal Doxorubicin and 4 differently formulated Clove powders (3 mg/kg + 150mg/kg). The duration of the experiment was 21 days. Formulated powder groups (Group V-VIII) exhibited a a remarkable decrease in nephralgic biomarkers like plasma creatinine, plasma albumin and plasma urea with the toxicant control group which revealed the nephralgic-protectivity of self-micro emulsifying formulation of Syzygium aromaticum-Clove extract against cardiac injury.
Honors - 2016-17
S.M Shohel
Executive in Pharma Industry
Thesis Title: Evaluation of Cardioprotective Effect of Allium sativum (Garlic) Through Self Micro-Emulsifying Drug Delivery System in Sodium Fluoride Treated Mice
Overview: Cardiovascular disease (CVD) is the leading cause of death globally. Despite the fact that some medications and mechanical methods are employed, natural products like herbs and spices are increasingly preferred for treating CVD because of their pharmacological benefits and lack of side effects. The purpose of this current study was to examine the potential cardioprotective effects of garlic extract through Self-micro Emulsifying Drug Delivery System (SMEDDS) on mice models using sodium fluoride (NaF) as a standard cardiotoxic drug. Four different SMEDDS formulations of garlic extract were prepared using different excipient ratios and underwent various evaluative tests like flow property, visual inspection, self-emulsification time, stability test, SEM analysis & Zeta potential in order to characterize all formulations and showed satisfactory results for all tests performed. Forty Swiss albino mice (20-30 g), were randomly divided into eight groups each of which consisted of five mice. Group I was the normal control group, where the animals received no treatment and Group II was defined as a toxicant control group treated with NaF orally at a dose of 12 mg/kg BWT daily. On the other hand, Group III was given raw Garlic extract only (50 mg/kg BWT) in contrast with Group IV, which was treated with both NaF + raw Garlic extract (same time, same dose used previously). Group V-VIII received orally NaF and 4 differently formulated Garlic powders (12 mg/kg + 90 mg/kg). The duration of the experiment was 28 days. Formulated powder groups (Group V-VIII) exhibited a remarkable decrease (p<0.05) in cardiac biomarkers like TC, LDL, and TG, whereas a remarkable increase in HDL was observed in these groups compared with the toxicant control group which revealed the cardio-protectivity of self-micro emulsifying formulation of garlic extract against cardiac injury.
- Institutional Email: arahman.phar@nstu.edu.bd
- Personal Email: arahmanphar5.nstu@gmail.com
- Mobile number: +880 1706477145
- Emergency Contact: +880 1816299081
- PABX:N/A
- Website:https://www.nstu.edu.bd/faculty-member.php?faculty=md-abdur-rahman-flq865
SOCIAL PROFILES
Department
Pharmacy
Noakhali Science and Technology University