Pharmacy

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EXTERNAL PROFILES

Associate Professor

Dr. Md. Shahid Sarwar

N/A

Pharmacy

BIOGRAPHY

Dr. Sarwar’s research interests lie at the intersection of Cancer Biology, Epigenetics, Pharmacogenetics, and Cancer Biomarkers. He has published over 80 peer-reviewed articles, which have collectively received more than 2,360 citations on Google Scholar (h-index: 27; i10-index: 47). He has presented his research outcomes in numerous international conferences across the USA, UK, Denmark, Japan, Hong Kong, and Bangladesh, and he is an active member of the American Association for Cancer Research (AACR) and the American Society for Pharmacology and Experimental Therapeutics (ASPET). He obtained his Ph.D. in 2019 from Hong Kong Baptist University, supported by the highly competitive Hong Kong PhD Fellowship Scheme (HKPFS), awarded by the Research Grants Council of Hong Kong. His doctoral research focused on the screening of potential cytotoxic compounds across a range of cancer cell lines—including colorectal, breast, pancreatic, melanoma, and lung cancers—with detailed investigations into structure-activity relationships and mechanisms of action, particularly in colorectal cancer cell lines and xenograft mouse models. Following his Ph.D., Dr. Sarwar completed a postdoctoral fellowship at Rutgers, The State University of New Jersey, USA, in the laboratory of Professor Ah-Ng Tony Kong, an internationally renowned scientist in cancer pharmacology and natural products. He was subsequently awarded the prestigious Cancer Research Training Award (CRTA) by the National Cancer Institute (NCI), National Institutes of Health (NIH), USA, in recognition of his continued excellence in cancer research. Dr. Sarwar has also led and contributed to several funded research projects, serving as Principal Investigator (PI) and Co-Principal Investigator (Co-PI) on the following studies: Principal Investigator (PI): 1. Study of the prevalence and genetic variants of MMP-1, MMP-3, MMP-7, and MMP-13 genes and their association with breast cancer risk in the Bangladeshi population Funding Source: Ministry of Science and Technology, Bangladesh (2020–21) 2. Association of genetic variants of matrix metalloproteinases with breast cancer in the Bangladeshi population Funding Source: Research Cell, Noakhali Science and Technology University (NSTU) (2020–21) Co-Principal Investigator (Co-PI): 1. Effect of fish supplementation on the nutritional status of adolescent girls: A randomized controlled trial in Bangladesh Funding Source: Bangladesh Agricultural Research Council (BARC) (2019–20) 2. Association of EGFR2, LSP1, ESR1, PIK3CA, and HOGG1 gene polymorphisms with breast cancer risk in Bangladeshi women Funding Source: University Grants Commission (UGC), Bangladesh (2019–20)

RESEARCH INTERESTS
Cancer Biology Epigenetics Metabolomics Pharmacogenetics

2023 - 2024

Visiting Fellow

National Cancer Institute (NCI)
National Institutes of Health (NIH), USA

2021 - 2023

Postdoctoral Fellow

Ernest Mario School of Pharmacy
Rutgers, The State University of New Jersey, USA

2016 - 2019

PhD

School of Chinese Medicine
Hong Kong Baptist University

2011 - 2013

M.Pharm in Clinical Pharmacy and Pharmacology

Pharmacy
Noakhali Science and Technology University

2006 - 2010

B.Pharm

Department of Pharmacy
Noakhali Science and Technology University

Last updated on 2025-10-10 15:37:24

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2024-03-04
RNA-Seq Data Analysis
Description: Enter Training Description
Organization: National Institutes of Health (NIH), USA
2023-12-26
Lab Safety and Bio-Safety Training
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Organization: National Institutes of Health (NIH), USA
2023-10-12
Safe Handling of Mice in Biomedical Research
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Organization: Rutgers, The State University of New Jersey, USA
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AWARDS AND ACHIEVEMENTS

1

Cancer Research Training Award (CRTA)

National Institutes of Health (NIH), USA

2

Postdoctoral Fellowship Award (Supported by NIH R01 Grant)

Rutgers, The State University of New Jersey, USA

3

Hong Kong PhD Fellowship Scheme (HKPFS)

Research Grants Council (RGC) of Hong Kong
2025
Journal

A Case‐Control Study on the Association Between MMP2 and MMP9 Genetic Polymorphisms and Breast Cancer.

Authors: Chowdhury P, Aziz MA, Akter T, Islam MS, Sarwar MS (Corresponding author).
Journal: Health Science Reports
DOI: 10.1002/hsr2.71123
2025
Journal

Dietary phytochemical indole-3-carbinol regulates metabolic reprogramming in mouse prostate tissue.

Authors: Peter RM, Sarwar MS* (Co-First Author), Wang L, Chou P, Wang C, Wang Y, Su X, Kong AN.
Journal: Pharmaceutical research
DOI: 10.1007/s11095-025-03820-8
2025
Journal

Authors: Kydd AR, Sarwar MS, Atiq S, Chelluri R, Gurram S, Chandran E, Simon N, ..., Apolo AB
Journal: Current Opinion in Oncology
DOI: 10.1097/CCO.0000000000001141
2025
Journal

Cancer-specific Regulation of Metabolic and Epigenetic Pathways by Dietary Phytochemicals.

Authors: Pan Y, Peter RM, Chou P, Dave PD, Xu J, Shanner A, Sarwar MS, Kong AN.
Journal: Pharmaceutical research
DOI: 10.1007/s11095-025-03898-0
2025
Journal

Exploring the Epigenetic and Metabolic Pathways for Antioxidant and Anti-Inflammatory Potentials of Tart Cherry Juice Concentrate

Authors: Xu J, Pan Y, Peter RM, Chou PJ, Dave PD, Shanner A, Sarwar MS, Kong AN.
Journal: Current Pharmacology Reports
DOI: 10.1007/s40495-025-00422-1
2025
Journal

Pharmacodynamics (PD), Pharmacokinetics (PK) and PK-PD Modeling of NRF2 Activating Dietary Phytochemicals in Cancer Prevention and in Health

Authors: Shannar A, Chou PJ, Peter R, Dave PD, Patel K, Pan Y, Xu J, Sarwar MS, Kong AN
Journal: Current Pharmacology Reports
2024
Journal

Triterpenoid ursolic acid regulates the environmental carcinogen benzo[a]pyrene-driven epigenetic and metabolic alterations in SKH-1 hairless mice for skin cancer interception.

Authors: Sarwar MS, Ramirez CN, Kuo HCD, Chou P, Wu R, Sargsyan D, Yang Y, Shannar A, Peter RM, Yin R, Wang Y, Su X, Kong AN
Journal: Carcinogenesis
DOI: 10.1093/carcin/bgae009
2024
Journal

Cyproheptadine inhibits in vitro and in vivo lung metastasis and drives metabolic rewiring.

Authors: Shannar* A, Sarwar MS* (Co-First Author), Dave PD, Chou PJ, Peter RM, Xu J, Pan Y, Rossi F, Kong AN.
Journal: Molecular Biology Reports
DOI: 10.1007/s11033-024-10033-6
2024
Journal

Epigenetics of Dietary Phytochemicals in Cancer Prevention: Fact or Fiction.

Authors: Chou PCJ, Peter RM, Shannar A, Pan Y, Dave PD, Xu J, Sarwar MS, Kong AN
Journal: The Cancer Journal
DOI: 10.1097/PPO.0000000000000742
2024
Journal

Histone deacetylase inhibitor belinostat regulates metabolic reprogramming in killing KRAS‐mutant human lung cancer cells.

Authors: Peter RM, Sarwar MS, Mostafa SZ, Wang Y, Su X, AN Kong.
Journal: Molecular Carcinogenesis
DOI: 10.1007/s11095-023-03595-w
2024
Journal

Altered trace elements, antioxidant vitamin C, and malondialdehyde levels are associated with the pathophysiology and development of pre-hepatic jaundice: A case-control study.

Authors: Dewan SMR , Das A, Ahmed ZL, Khan SA, Nasim R, Sarwar MS, Islam MS, Islam MR.
Journal: SAGE Open Medicine
DOI: 10.1177/20503121241291977
2023
Journal

An update on potential molecular biomarkers of dietary phytochemicals targeting lung cancer interception and prevention.

Authors: Peter RM, Chou PJ, Shannar A, Patel K, Pan Y, Dave PD, Xu J, Sarwar MS, Kong AN
Journal: Pharmaceutical research
DOI: 10.1007/s11095-023-03595-w
2023
Journal

Metabolic rewiring and epigenetic reprogramming in leptin receptor-deficient db/db diabetic nephropathy mice.

Authors: Sarwar MS, Cheng D, Peter RM, Shannar A, Chou P, Wang L, Wu R, Sargsyan D, Goedken M, Wang Y, Su X, Hart RP, Kong AN
Journal: European Journal of Pharmacology
DOI: 10.1016/j.ejphar.2023
2023
Journal

Metabolomic, DNA methylomic, and transcriptomic profiling of suberoylanilide hydroxamic acid effects on LPS-exposed lung epithelial cells.

Authors: Chou PJ*, Sarwar MS* (Co-First Author), Wang L, Wu R, Li S, Hudlikar RR, Wang Y, Su X, Kong AN.
Journal: Cancer Prevention Research
DOI: 10.1158/1940-6207.CAPR-22-0384
2023
Journal

Association of MMP1 gene polymorphisms with breast cancer risk: A narrative review.

Authors: Akter T, Aziz MA, Islam MS, Sarwar MS* (Corresponding author)
Journal: Health Science Reports
DOI: 10.1002/hsr2.1607
2022
Journal

PTEN-knockout regulates metabolic rewiring and epigenetic reprogramming in prostate cancer and chemoprevention by triterpenoid ursolic acid.

Authors: Wang L, Wang C, Sarwar MS, Chou P, Wang Y, Su X, Kong AN.
Journal: FASEB Journal
DOI: 10.1096/fj.202201195R
2022
Journal

Butyrate Drives Metabolic Rewiring and Epigenetic Reprogramming in Human Colon Cancer Cells.

Authors: Wang L, Shannar AAF, Wu R, Chou P, Sarwar MS, Kuo H, Peter RM, Wang Y, Su X, Kong AN.
Journal: Mol Nutr Food Res
DOI: 10.1002/mnfr.202200028
2022
Journal

Nfe2l2 Regulates Metabolic Rewiring and Epigenetic Reprogramming in Mediating Cancer Protective Effect by Fucoxanthin.

Authors: Wang L, Wu R, Sargsyan D, Su S, Kuo HC, Li S, Chou P, Sarwar MS, Phadnis A, Wang Y, Su X, Kong AN.
Journal: Journal of the American Association of Pharmaceutical Scientists (AAPS)
DOI: 10.1208/s12248-022-00679-0
2022
Journal

DNA Methylome and Transcriptome Study of Triterpenoid CDDO in TPA-Mediated Skin Carcinogenesis Model.

Authors: Kuo HCD, Wu R, Sarwar MS, Zheng M, Wang C, Sargsyan D, Suh N
Journal: Journal of the American Association of Pharmaceutical Scientists (AAPS)
DOI: 10.1208/s12248-022-00763-5
2022
Journal

A New Frontier in Studying Dietary Phytochemicals in Cancer and in Health: Metabolic and Epigenetic Reprogramming.

Authors: Shannar A, Sarwar MS, Kong AN.
Journal: Preventive Nutrition and Food Science
DOI: 10.3746/pnf.2022.27.4.335
2022
Journal

Exploring the role of senescence inducers and senotherapeutics as targets for anticancer natural products.

Authors: Mamun AA, Sufian MA, Uddin MS, Sumsuzzman DM, Jeandet P, Islam MS, Zhang HJ, Kong AN, Sarwar MS (Corresponding author).
Journal: European Journal of Pharmacology
DOI: 10.1016/j.ejphar.2022.174991
Journal

Preparation and quality characterization of marine small pelagic fish powder: A novel ready-to-use nutritious food product for vulnerable populations.

Authors: Mamun AA, Bhowmik S, Sarwar MS, Akter S, Pias T, Zakaria MUMA, Islam MM, Egna H, Evans F, Wahab MA, Thilsted SH, Little DC.
Journal: Measurement: Food
DOI: 10.1016/j.meafoo.2022.100067
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SOCIAL PROFILES

Department

Pharmacy

Noakhali Science and Technology University